منابع مشابه
Transcriptome sequencing in prostate cancer identifies inter-tumor heterogeneity
Given the dearth of gene mutations in prostate cancer, [1] ,[2] it is likely that genomic rearrangements play a significant role in the evolution of prostate cancer. However, in the search for recurrent genomic alterations, "private alterations" have received less attention. Such alterations may provide insights into the evolution, behavior, and clinical outcome of an individual tumor. In a rec...
متن کاملHuman Cancer Modeling: Recapitulating Tumor Heterogeneity Towards Personalized Medicine
Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
متن کاملHuman Cancer Modeling: Recapitulating Tumor Heterogeneity Towards Personalized Medicine
Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
متن کاملTumor heterogeneity.
In 1977, Dan Dexter and I, with colleagues at Roger Williams General Hospital, submitted a manuscript to Cancer Research in which we reported the isolation of four distinct tumor subpopu lations from a single, spontaneously arising mouse mammary cancer. We speculated that these subpopulations were evidence for intraneoplastic heterogeneity and that heterogeneity was a general phenomenon, knowle...
متن کاملComparative Analysis of Intra-and Inter Populational Heterogeneity of the Essential Oils in White Savory Plants
White savory(Satureja mutica Fisch & C.A.Mey.) is one of the most widely used medicinal plants in food processing, pharmaceutical and cosmetic industry due to the strongly scented and presence of phenolic compounds such as carvacrol and thymol. This experiment was carried out to evaluate the levels of inter and intra-populations variability of essential oil compositions of S. mutica grown in no...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Human Vaccines & Immunotherapeutics
سال: 2012
ISSN: 2164-5515,2164-554X
DOI: 10.4161/hv.21203